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Short-RInChIKey=SA-FUHFF-UHFFFADPSC-NDLIRBZKZS-UHFFFADPSC-NUHFF-NUHFF-NUHFF-ZZZ Dataset
To a suspension of 4-methylbenzenesulfonyl chloride (20.0 g, 105 mmol, 1.00 equiv) in 133 mL acetone cooled to 0 °C, a solution of sodium;azide (10.2 g, 157 mmol, 1.50 equiv)... -
Short-RInChIKey=SA-FUHFF-UHFFFADPSC-HVSWCKSDIC-UHFFFADPSC-NUHFF-NUHFF-NUHFF-ZZZ Dataset
Under an argon atmosphere, n-butyllithium (1.58 g, 9.88 mL, 24.7 mmol, 2.50 M in n-hexane, 8.00 equiv.) was added dropwise over 10 min to a solution of... -
Short-RInChIKey=SA-FUHFF-UHFFFADPSC-RAEZJUWRAY-UHFFFADPSC-NUHFF-NUHFF-NUHFF-ZZZ Dataset
A mixture of 3-chloro-5-(trifluoromethyl)pyridin-2-amine (150 mg, 763 μmol, 1.00 equiv), 2-bromo-1-(2-fluorophenyl)ethanone (166 mg, 763 μmol, 1.00 equiv) and sodium hydrogen... -
Short-RInChIKey=SA-FUHFF-UHFFFADPSC-ATHNSQRFCX-UHFFFADPSC-NUHFF-NUHFF-NUHFF-ZZZ Dataset
A mixture of 3-chloro-5-(trifluoromethyl)pyridin-2-amine (150 mg, 763 μmol, 1.00 equiv), 2-bromo-1-phenylethanone (152 mg, 763 μmol, 1.00 equiv) and sodium hydrogen carbonate... -
Short-RInChIKey=SA-FUHFF-UHFFFADPSC-LHUTUFIEQF-UHFFFADPSC-NUHFF-NUHFF-NUHFF-ZZZ Dataset
A mixture of 3-chloro-5-(trifluoromethyl)pyridin-2-amine (500 mg, 2.54 mmol, 1.00 equiv), 2-bromo-1-(4-fluorophenyl)ethanone (524 mg, 2.42 mmol, 0.950 equiv) and sodium... -
Short-RInChIKey=SA-FUHFF-UHFFFADPSC-FXWFZIRWWN-UHFFFADPSC-NUHFF-NUHFF-NUHFF-ZZZ Dataset
The starting material 2-nitrobenzaldehyde (5.00 g, 33.1 mmol, 1.00 equiv) was dissolved in 22 mL of a 9:1 mixture of EtOH/H2O, followed by iron (9.24 g, 165 mmol, 5.00 equiv)... -
Short-RInChIKey=SA-FUHFF-UHFFFADPSC-OWMJAQBUFV-UHFFFADPSC-NUHFF-NUHFF-NUHFF-ZZZ Dataset
A solution of the starting material 2-aminobenzaldehyde (107 mg, 884 μmol, 1.00 equiv) and N,N-diethylethanamine (102 mg, 140 μL, 1.00 mmol, 1.14 equiv) in dichloromethane... -
Short-RInChIKey=SA-FUHFF-UHFFFADPSC-VIRCVYOPUF-UHFFFADPSC-NUHFF-LGEIA-NUHFF-ZZZ Dataset
1,8-bis[(E)-2-(4-pyridyl)ethenyl]naphthalene (0.10 g, 0.30 mmol, 1.00 equiv.) and iodomethane (0.17 g, 1.20 mmol, 4.00 equiv.) were suspended in DMF (10 ml), the mixture was... -
Short-RInChIKey=SA-FUHFF-UHFFFADPSC-IXIHDVSFIR-UHFFFADPSC-NUHFF-NUHFF-NUHFF-ZZZ Dataset
TEMPO (1 g, 6.4 mmol), 2-bromo-2-methyl propionic acid or 4-(1-bromoethyl)benzoic acid (1.2 eq.), Cu (1.2 eq.), CuBr (1.2 eq.) and a stir bar were added into a three neck... -
Short-RInChIKey=SA-FUHFF-UHFFFADPSC-GLVNZYODMK-UHFFFADPSC-NUHFF-NSOPS-NUHFF-ZZZ Dataset
The reaction was performed under inert atmosphere using Schlenk techniques. Methyl levulinate (3.99 g, 3.80 mL, 30.7 mmol, 1.0 equiv) was dissolved in dry chloroform (10 mL)... -
Short-RInChIKey=SA-FUHFF-UHFFFADPSC-UNWKVSDABP-UHFFFADPSC-NUHFF-NUHFF-NUHFF-ZZZ Dataset
2-Bromothiophene (1.48 g, 9.11 mmol, 2.20 equiv) and Magnesium (240 mg, 9.11 mmol, 2.20 equiv) were suspended in THF (10 mL) and the mixture was heated to 55 °C for 1 h.... -
Short-RInChIKey=SA-FUHFF-UHFFFADPSC-WCDUEUSLTD-UHFFFADPSC-NUHFF-NUHFF-NUHFF-ZZZ Dataset
To a solution of ocytyl magnesium bromide (1 eq., 50mL, 100.00 mmol, 2M) in diethyl ether was added furfural (1 eq. 7.5 mL, 90.55 mmol) dropwise at 0 °C with stirring. After... -
Short-RInChIKey=SA-FUHFF-UHFFFADPSC-GUZYJTKHMS-UHFFFADPSC-NUHFF-NBMBM-NUHFF-ZZZ Dataset
A solution of the ester (100 mg, 233 μmol, 1.00 equiv) and potassium hydroxide (200 mg, 3.57 mmol, 15.3 equiv) in methanol (15 mL) was refluxed for 1 h. After cooling down to... -
Short-RInChIKey=SA-FUHFF-UHFFFADPSC-RJKOTIRDIV-UHFFFADPSC-NUHFF-NUHFF-NUHFF-ZZZ Dataset
The propellane solution (1.00 mL, 0.40 M in Et2O, 400 μmol, 2.00 equiv) was added to a solution of the 1-methyl-4-[(4-methylphenyl)disulfanyl]benzene (49.3 mg, 200 μmol, 1.00... -
Short-RInChIKey=SA-FUHFF-UHFFFADPSC-MRDPMFJFXN-UHFFFADPSC-NUHFF-NUHFF-NUHFF-ZZZ Dataset
The propellane solution (1.00 mL, 0.44 M in Et2O, 437 μmol, 1.00 equiv) was added to a solution of (phenyldisulfanyl)benzene (143 mg, 655 μmol, 1.50 equiv) and... -
Short-RInChIKey=SA-FUHFF-UHFFFADPSC-MRDPMFJFXN-UHFFFADPSC-NUHFF-NUHFF-NUHFF-ZZZ Dataset
The propellane solution (28.9 mg, 1.00 mL, 437 μmol, 1.00 equiv) was added to a solution of (phenyldisulfanyl)benzene (143 mg, 655 μmol, 1.50 equiv) and... -
Short-RInChIKey=SA-FUHFF-UHFFFADPSC-JMIIRMHBYM-UHFFFADPSC-NUHFF-MZOEC-NUHFF-ZZZ Dataset
In a vial, (E)-2,3,3-trimethyl-5-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-en-1-yl)-3H-indole (403 mg, 801 µmol, 1.00 equiv.) and methyl iodide (1.137 g, 8.01 mmol, 10.0... -
Short-RInChIKey=SA-FUHFF-UHFFFADPSC-OGJNIRVMBU-UHFFFADPSC-NUHFF-MYXSC-NUHFF-ZZZ Dataset
In a vial, (E)-1,2,3,3-tetramethyl-5-(1H,2H-perfluoroct-1-en-1-yl)-3H-indolium iodide (131 mg, 203 µmol, 1.00 equiv.) and Vilsmeier-Haack salt (32.9 mg, 91.5 µmol, 0.45... -
Short-RInChIKey=SA-FUHFF-UHFFFADPSC-JTJKNVJLPW-UHFFFADPSC-NUHFF-NUHFF-NUHFF-ZZZ Dataset
In a vial, 4-(dimethylamino)benzaldehyde (96.0 mg, 643 μmol, 1.20 equiv) was dissolved in toluene (5.00 mL) and 2-amino-4-chlorobenzenethiol (85.6 mg, 536 μmol, 1.00 equiv)... -
Short-RInChIKey=SA-FUHFF-UHFFFADPSC-IRICWKXXVN-UHFFFADPSC-NUHFF-NUHFF-NUHFF-ZZZ Dataset
Ethyl 4-aminobenzoate (1.50 g, 9.08 mmol, 1.00 equiv) was dissolved in a mixture of fluoroboric acid (48 wt% in water, 3.1 mL) and water (3.7 mL). After cooling to 0 °C,...